Nitric oxide-generating vasodilators inhibit mitogenesis and proliferation of BALBc 3T3 fibroblasts by a cyclic GMP-independent mechanism

Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells.

Uttam Garg, Aviv Hassid · Journal of Clinical Investigation · 1989 · 2.2K citations · Full text

Medicine, Pharmacology, Biochemical Pharmacology +12

Nitric oxide: A cytotoxic activated macrophage effector molecule

John B. Hibbs, Read R. Taintor, Zdenek Vavrin et al. · Biochemical and Biophysical Research Communications · 1988 · 2K citations

Life Sciences, Cell Biology, Immunology +12

Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells.

Dennis J. Stuehr, Carl Nathan · The Journal of Experimental Medicine · 1989 · 1.8K citations · Full text

Life Sciences, Cancer Biology, Cell Biology +16

Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates.

L J Ignarro, Howard Lippton, Jo C. W. Edwards et al. · Journal of Pharmacology and Experimental Therapeutics · 1981 · 1.6K citations

Life Sciences, Biophysics, Physiology +6

Advances in Cyclic Nucleotide Research.

Annals of Internal Medicine · 1980 · 1.5K citations

Life Sciences, Biochemistry, Cellular Metabolism +8