Zdenek Vavrin

Nitric oxide: A cytotoxic activated macrophage effector molecule

John B. Hibbs, Read R. Taintor, Zdenek Vavrin et al. · Biochemical and Biophysical Research Communications · 1988 · 2K citations

Inflammation, Reactive Nitrogen Specie, Nitric Oxide +6

Macrophage Cytotoxicity: Role for L-Arginine Deiminase and Imino Nitrogen Oxidation to Nitrite

John B. Hibbs, Read R. Taintor, Zdenek Vavrin · Science · 1987 · 1.5K citations

L-arginine is required for expression of the activated macrophage effector mechanism causing selective metabolic inhibition in target cells.

John B. Hibbs, Zdenek Vavrin, Read R. Taintor · The Journal of Immunology · 1987 · 935 citations · Full text

Selective Metabolic Inhibition, Creatine Biosynthesis, Immunology +18

Evidence for cytokine-inducible nitric oxide synthesis from L-arginine in patients receiving interleukin-2 therapy.

John B. Hibbs, Christof Westenfelder, Read R. Taintor et al. · Journal of Clinical Investigation · 1992 · 490 citations · Full text

Interleukin-2 Therapy, Il-2 Therapy, Lung Inflammation +18

Iron depletion: Possible cause of tumor cell cytotoxicity induced by activated macrophages

John B. Hibbs, Read R. Taintor, Zdenek Vavrin · Biochemical and Biophysical Research Communications · 1984 · 180 citations

Inflammation, Immunotoxicology, Tumor Cell Cytotoxicity +14