New England Journal of Medicine · 1983 · 817 citations · 9 references
Veterinary MedicineImmunologyInfectious DiseasesImmunology Of Infectious DiseasesInfectious Disease EpidemiologyMedical EntomologyLyme DiseaseTick BiologyTick-borne DiseasesEtiologic HypothesisIxodes Tick VectorsLyme Disease EpidemiologyTick-borne Disease InvestigationTick-borne Pathogens
We isolated spirochetes from the blood of 2 of 36 patients in Long Island and Westchester County, New York, who had signs and symptoms suggestive of Lyme disease. The spirochetes were morphologically similar and serologically identical to organisms recently found to infect lxodes dammini ticks, which are endemic to the area and have been epidemiologically implicated as vectors of Lyme disease. In both patients, there was a rise in specific antispirochetal antibodies in paired specimens of serum. We conclude that the l. dammini spirochete has an etiologic role in Lyme disease.
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Lyme Disease—a Tick-Borne Spirochetosis?
Willy Burgdorfer, Alan G. Barbour, Stanley F. Hayes et al. · Science · 1982 · 2.9K citations · Full text
Erythema Chronicum Migrans and Lyme Arthritis
Allen C. Steere, Malawista Se, Shaun Ruddy et al. · Annals of Internal Medicine · 1977 · 688 citations
Neurologic Abnormalities of Lyme Disease
Louis Reik, Allen C. Steere, Nicholas H. Bartenhagen et al. · Medicine · 1979 · 465 citations