Loss of RhoA expression prevents proliferation and metastasis of SPCA1 lung cancer cells in vitro

Rho GTPases are over-expressed in human tumors

Gerhard Fritz, Ingo Just, Bernd Kaina · International Journal of Cancer · 1999 · 662 citations

Cdc42–MRCK and Rho–ROCK signalling cooperate in myosin phosphorylation and cell invasion

Simon Wilkinson, Hugh F. Paterson, Christopher J. Marshall · Nature Cell Biology · 2005 · 384 citations

Signal Transduction, Signaling Pathway, Natural Sciences +11

The Rho kinase inhibitor fasudil inhibits tumor progression in human and rat tumor models

Ying Han, Sandra L. Biroc, Weiwei Li et al. · Molecular Cancer Therapeutics · 2006 · 178 citations · Full text

Rapid Actin Transport During Cell Protrusion

Daniel Zicha, Ian M. Dobbie, Mark Holt et al. · Science · 2003 · 176 citations

Inhibition of intrahepatic metastasis of human hepatocellular carcinoma by Rho-associated protein kinase inhibitor Y-27632

Masaaki Takamura · Hepatology · 2001 · 117 citations

Oncology, Hepatology, Human Hepatocellular Carcinoma +15