Induction of cell cycle arrest and apoptosis in human cervix carcinoma cells during therapy by cisplatin

Apaf-1, a Human Protein Homologous to C. elegans CED-4, Participates in Cytochrome c–Dependent Activation of Caspase-3

Hua Zou, William J. Henzel, Xuesong Liu et al. · Cell · 1997 · 3.1K citations · Full text

Life Sciences, Biology, Molecular Biology +10

A Detergent‐trypsin method for the preparation of nuclei for flow cytometric DNA analysis

Lars L. Vindeløv, Ib Jarle Christensen, Nis I. Nissen · Cytometry · 1983 · 1.7K citations · Full text

Medicine, Cell Biology, Oncology +12

Adducts of the antitumor drug cis-diamminedichloroplatinum(II) with DNA: formation, identification, and quantitation

Anne Marie J. Fichtinger-Schepman, J. L. VAN DER VEER, Jeroen H. J. Den Hartog et al. · Biochemistry · 1985 · 1K citations

Medicine, Oncology, Pharmacology +8

Cytochrome c and dATP-mediated Oligomerization of Apaf-1 Is a Prerequisite for Procaspase-9 Activation

Ayman Saleh, Srinivasa M. Srinivasula, Samir Acharya et al. · Journal of Biological Chemistry · 1999 · 503 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Analysis of Events Associated With Cell Cycle Arrest at G2 Phase and Cell Death Induced by Cisplatin

Christine M. Sorenson, Michael A. Barry, Alan Eastman · JNCI Journal of the National Cancer Institute · 1990 · 451 citations

Life Sciences, Cell Biology, Oncology +17