Concepedia

Antinociceptive activity of<i>Syzygium cumini</i>leaves ethanol extract on orofacial nociception protocols in rodents

Jullyana de Souza Siqueira Quintans, Renan Guedes de Brito, Pedro Gregório Vieira Aquino, Paulo Henrique Barcellos França, Pollyana S. Siqueira-Lima, Antônio Euzébio Goulart Santana, Êurica Adélia Nogueira Ribeiro, Marcos José Salvador, João Xavier de Araújo‐Júnior, Lucindo José Quintans‐Júnior

Pharmaceutical Biology · 2014 · 17 citations · 20 references

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Abstract

We can suggest that the antinociceptive effect of the EE is mediated by peripheral mechanisms, possibly involving KATP channels and the nitric oxide pathways. These effects appear to be related to the presence of flavonoids compounds, such as quercetin.

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