AZT induces oxidative damage to cardiac mitochondria: Protective effect of vitamins C and E

Normal oxidative damage to mitochondrial and nuclear DNA is extensive.

Christoph Richter, J W Park, B N Ames · Proceedings of the National Academy of Sciences · 1988 · 1.7K citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase.

P A Furman, James A. Fyfe, M H St Clair et al. · Proceedings of the National Academy of Sciences · 1986 · 1.3K citations · Full text

Life Sciences, Molecular Biology, Pharmacology +8

Vitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowance.

Mark N. Levine, Cathy Conry‐Cantilena, Y Wang et al. · Proceedings of the National Academy of Sciences · 1996 · 1.3K citations

Agriculture, Nutritional Sciences, Pharmacokinetics +17

Evaluation of 2′,7′-Dichlorofluorescin and Dihydrorhodamine 123 as Fluorescent Probes for Intracellular H2O2 in Cultured Endothelial Cells

James A. Royall, Harry Ischiropoulos · Archives of Biochemistry and Biophysics · 1993 · 1.1K citations

Life Sciences, Cell Biology, Pharmacology +14

Lipoperoxides in plasma as measured by liquid-chromatographic separation of malondialdehyde-thiobarbituric acid adduct.

Steven Wong, J A Knight, S M Hopfer et al. · Clinical Chemistry · 1987 · 818 citations

Life Sciences, Biochemistry, Pharmacology +15