Intracerebroventricular interleukin-6, macrophage inflammatory protein-1β and IL-18: pyrogenic and PGE2-mediated?

PHARMACOLOGICAL EFFECTS PRODUCED BY INTRACEREBRAL INJECTION OF DRUGS IN THE CONSCIOUS MOUSE

Thomas J. Haley, WF McCormick · British Journal of Pharmacology and Chemotherapy · 1957 · 1.5K citations · Full text

Medicine, Neuroscience, Pharmacology +12

Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration

Robert Langenbach, Scott G. Morham, Howard F. Tiano et al. · Cell · 1995 · 1.1K citations · Full text

Life Sciences, Biochemistry, Pharmacology +16

Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse

Scott G. Morham, Robert Langenbach, Charles D. Loftin et al. · Cell · 1995 · 1.1K citations · Full text

Medicine, Molecular Biology, Molecular Genetics +13

Macrophages secrete a novel heparin-binding protein with inflammatory and neutrophil chemokinetic properties.

Stephen D. Wolpe, G. Davatelis, Barbara Sherry et al. · The Journal of Experimental Medicine · 1988 · 580 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Interleukin-18 (IFNgamma-inducing factor) induces IL-8 and IL-1beta via TNFalpha production from non-CD14+ human blood mononuclear cells.

Adrian Puren, Giamila Fantuzzi, Yun Gu et al. · Journal of Clinical Investigation · 1998 · 553 citations · Full text

Life Sciences, Cell Biology, Immunology +16