A One-Pot Tandem Pictet-Spengler-Diels-Alder Synthesis of Apoyohimbines from 3-Carbomethoxy-2-(formylmethyl)-3-sulfolene

Diastereo- and enantio-selectivity in the Pictet–Spengler reaction

Patrick D. Bailey, Sean P. Hollinshead, Neil McLay et al. · Journal of the Chemical Society Perkin Transactions 1 · 1993 · 90 citations

Pharmacy, Chemistry, Medicinal Chemistry +11

Unified strategy for synthesis of indole and 2-oxindole alkaloids

Stephen F. Martin, J. E. Hunter, B. BENAGE et al. · Journal of the American Chemical Society · 1991 · 88 citations

Natural Sciences, Chemistry, Medicinal Chemistry +10

Chirality in α- and β-adrenoceptor agonists and antagonists

Robert Ruffolo · Tetrahedron · 1991 · 86 citations

Medicine, Medicinal Chemistry, Pharmacology +9

Efficient Preparation of Useful 1,2-Substituted Electron-Deficient Dienes from Sulpholenes and Their Use in Intramolecular Diels-Alder Reactions: A General Approach to Alkaloids

John Leonard, Stephen P. Fearnley, Deirdre M. B. Hickey · Synlett · 1992 · 38 citations

Natural Sciences, Chemistry, Medicinal Chemistry +10

A short synthesis of apoyohimbines via a sulfolene based intramolecular Diels-Alder reaction

John Leonard, Diana Appleton, Stephen P. Fearnley · Tetrahedron Letters · 1994 · 21 citations

Natural Sciences, Chemistry, Medicinal Chemistry +5