Concepedia

Novel Molecular Type of<i>Clostridium difficile</i>in Neonatal Pigs, Western Australia

Michele M. Squire, Glen P. Carter, Kate E. Mackin, Anjana Chakravorty, Torbjörn Norén, Briony Elliott, Dena Lyras, Thomas V. Riley

Emerging infectious diseases · 2013 · 44 citations · 12 references

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Abstract

Clostridium difficile causes neonatal enteritis in piglets; strains of PCR ribotype 078 are most commonly identified. We investigated C. difficile prevalence in piglets in Australia and isolated a novel strain with a unique pathogenicity locus. In a mouse infection model, this strain produced more weight loss than did a ribotype 078 strain.

References

12

Velvet: Algorithms for de novo short read assembly using de Bruijn graphs

Daniel R. Zerbino, Ewan Birney · Genome Research · 2008 · 9.7K citations · Full text

, , +14

Toxin B is essential for virulence of Clostridium difficile

Dena Lyras, Jennifer R. O’Connor, Pauline M. Howarth et al. · Nature · 2009 · 753 citations · Full text

, , +14

Emergence of<i>Clostridium difficile</i>Infection Due to a New Hypervirulent Strain, Polymerase Chain Reaction Ribotype 078

Abraham Goorhuis, Dennis Bakker, Jeroen Corver et al. · Clinical Infectious Diseases · 2008 · 642 citations · Full text

, , +11

PCR Targeted to the 16S-23S rRNA Gene Intergenic Spacer Region of <i>Clostridium difficile</i> and Construction of a Library Consisting of 116 Different PCR Ribotypes

Simon Stubbs, John Brazier, G. L. O’Neill et al. · Journal of Clinical Microbiology · 1999 · 542 citations · Full text

, , +14

A Mouse Model of Clostridium difficile–Associated Disease

Xinhua Chen, Kianoosh Katchar, Jeffrey D. Goldsmith et al. · Gastroenterology · 2008 · 525 citations

, , +14