Pauline M. Howarth

Toxin B is essential for virulence of Clostridium difficile

Dena Lyras, Jennifer R. O’Connor, Pauline M. Howarth et al. · Nature · 2009 · 753 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +14

Defining the Roles of TcdA and TcdB in Localized Gastrointestinal Disease, Systemic Organ Damage, and the Host Response during Clostridium difficile Infections

Glen P. Carter, Anjana Chakravorty, Tu Anh Pham Nguyen et al. · mBio · 2015 · 339 citations · Full text

Veterinary Medicine, Infectious Diseases, Pathobiology +17

The Anti-Sigma Factor TcdC Modulates Hypervirulence in an Epidemic BI/NAP1/027 Clinical Isolate of Clostridium difficile

Glen P. Carter, Gill Douce, Revathi Govind et al. · PLoS Pathogens · 2011 · 155 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +13

Binary Toxin Production in <i>Clostridium difficile</i> Is Regulated by CdtR, a LytTR Family Response Regulator

Glen P. Carter, Dena Lyras, David L. Allen et al. · Journal of Bacteriology · 2007 · 143 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +17

Environmental Response and Autoregulation of <i>Clostridium difficile</i> TxeR, a Sigma Factor for Toxin Gene Expression

Nagraj Mani, Dena Lyras, Lisa Barroso et al. · Journal of Bacteriology · 2002 · 137 citations · Full text

Life Sciences, Genetics, Microbiology +17