Multiple peptide synthesis using cellulose-based carriers: Synthesis of substance P - diastereoisomers and their histamine-releasing activity

General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids.

Richard A. Houghten · Proceedings of the National Academy of Sciences · 1985 · 1.7K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Use of peptide synthesis to probe viral antigens for epitopes to a resolution of a single amino acid.

H. Mario Geysen, Rob H. Meloen, S J Barteling · Proceedings of the National Academy of Sciences · 1984 · 1.5K citations · Full text

Life Sciences, Biochemistry, Immunology +17

Solid-phase synthesis of protected peptide fragments using a trialkoxy-diphenyl-methylester resin.

H Rink · Tetrahedron Letters · 1987 · 856 citations

Natural Sciences, Biochemistry, Chemistry +7

Regulation of Gi and Go by mastoparan, related amphiphilic peptides, and hydrophobic amines. Mechanism and structural determinants of activity.

Tsutomu Higashijima, John P. Burnier, Elliott M. Ross · Journal of Biological Chemistry · 1990 · 602 citations · Full text

Life Sciences, Biochemistry, Pharmacology +16

Simultaneous multiple peptide synthesis under continuous flow conditions on cellulose paper discs as segmental solid supports

Ronald Frank, Renate Döring · Tetrahedron · 1988 · 217 citations

Natural Sciences, Chemical Engineering, Materials Science +7