BLOCKADE OF THE CD40/CD154 PATHWAY ENHANCES T-CELLDEPLETED ALLOGENEIC BONE MARROW ENGRAFTMENT UNDER NONMYELOABLATIVE AND IRRADIATION-FREE CONDITIONING THERAPY

Abstract

Donor T cells facilitate bone marrow engraftment under nonmyeloablative and irradiation-free conditioning therapy, and the blocking the CD40/CD154 pathway can replace donor T cells to promote TDBM engraftment.