Cell cycle perturbations in acute myeloid leukemia samples following in vitro exposures to therapeutic agents

Participation of p53 protein in the cellular response to DNA damage.

Michael B. Kastan, Onyinye Onyekwere, D Sidransky et al. · PubMed · 1991 · 3.8K citations

Dna Damage, Chemoprevention Strategy, Apoptosis +17

WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis.

Wafik S. El‐Deiry, J. Wade Harper, O'Connor Pm et al. · PubMed · 1994 · 2K citations

Tumor Biology, P53 Function, Wild-type P53 +14

High expression of bcl-2 protein in acute myeloid leukemia cells is associated with poor response to chemotherapy

Lydia Campos, JP Rouault, Odile Sabido et al. · Blood · 1993 · 777 citations · Full text

p53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies

Eric Wattel, Claude Preudhomme, B Hecquet et al. · Blood · 1994 · 580 citations · Full text

UCN-01: a Potent Abrogator of G2 Checkpoint Function in Cancer Cells With Disrupted p53

Qizhi Wang, Songqing Fan, Alan Eastman et al. · JNCI Journal of the National Cancer Institute · 1996 · 447 citations · Full text