Organic & Biomolecular Chemistry · 2009 · 174 citations · 21 references
Life SciencesBiochemistryBiotechnologyBiomaterialsProtein EngineeringProteomicsBioconjugation ChemistryProtein ChemistryProtein PurificationProtein SeparationProtein-based BiomaterialsSurface ImmobilizationBioconjugationBioconjugation Method DevelopmentBioconjugation ReagentsFunctionalizationSolid SupportsThiol ChemistryThiol Functionalization
The easy functionalization of tags and solid supports with the vinyl sulfone function is a valuable tool in omic sciences that allows their coupling with the amine and thiol groups present in the proteogenic residues of proteins, in mild and green conditions compatible with their biological function.
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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
Ulrich K. Laemmli · Nature · 1970 · 251.6K citations