Concepedia

Factors affecting the deamidation of vancomycin in aqueous solutions

Amy S. Antipas, David Vander Velde, V.J. Stella

International Journal of Pharmaceutics · 1994 · 18 citations · 15 references

DOI

Concepts

References

15

Deamidation, isomerization, and racemization at asparaginyl and aspartyl residues in peptides. Succinimide-linked reactions that contribute to protein degradation.

Terrence L. Geiger, Steven Clarke · Journal of Biological Chemistry · 1987 · 1.3K citations · Full text

, , +16

[14] Cleavage at AsnGly bonds with hydroxylamine

Paul Börnstein, Gary Balian · Methods in enzymology on CD-ROM/Methods in enzymology · 1977 · 417 citations

, , +9

Propensity for spontaneous succinimide formation from aspartyl and asparaginyl residues in cellular proteins

Steven Clarke · International journal of peptide & protein research · 1987 · 335 citations

, , +16

Structure of vancomycin and its complex with acetyl-D-alanyl-D-alanine

George M. Sheldrick, Peter G. Jones, Olga Kennard et al. · Nature · 1978 · 291 citations

, , +7

Chemical Pathways of Peptide Degradation. II. Kinetics of Deamidation of an Asparaginyl Residue in a Model Hexapeptide

Kamlesh C. Patel, Ronald T. Borchardt · Pharmaceutical Research · 1990 · 279 citations

, , +17