Production of (R)-1-(1,3-dithian-2-yl)propan-2-ol by microbial reduction

Abstract

The reduction of several selected carbonyl compounds with growing cultures of Streptomyces sp., Aspergillus niger, and Geotrichum candidum has been studied. The production of (R)-1-(1,3-dithian-2-yl)propan-2-ol of high enantiomeric purity has been achieved by reduction of dithianylacetone with a Streptomyces sp.