Concepedia

The Metabotropic Glutamate 5 Receptor Antagonist 3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]-pyridine Reduces Ethanol Self-Administration in Multiple Strains of Alcohol-Preferring Rats and Regulates Olfactory Glutamatergic Systems

Michael S. Cowen, Elvan Djouma, Andrew J. Lawrence

Journal of Pharmacology and Experimental Therapeutics · 2005 · 121 citations · 73 references

DOI

Concepts

References

73

2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist

F. Gasparini, Kurt Lingenhöhl, Natacha Stoehr et al. · Neuropharmacology · 1999 · 720 citations

, , +7

Distribution of metabotropic glutamate receptor mGluR5 immunoreactivity in rat brain

Carmelo Romano, Michael A. Sesma, Colin T. McDonald et al. · The Journal of Comparative Neurology · 1995 · 673 citations

, , +15

Mice Lacking Metabotropic Glutamate Receptor 5 Show Impaired Learning and Reduced CA1 Long-Term Potentiation (LTP) But Normal CA3 LTP

Youming Lu, Zhengping Jia, Christopher Janus et al. · Journal of Neuroscience · 1997 · 630 citations · Full text

, , +17

The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption

Rainer Spanagel, Gurudutt Pendyala, Carolina Abarca et al. · Nature Medicine · 2004 · 589 citations

, , +16

Reinforcing and locomotor stimulant effects of cocaine are absent in mGluR5 null mutant mice

Cristiano Chiamulera, Mark P. Epping-Jordan, Alessandro Zocchi et al. · Nature Neuroscience · 2001 · 549 citations

, , +14