Journal of the American Chemical Society · 2008 · 92 citations · 15 references
Natural SciencesChemistryMedicinal ChemistryOrganic ChemistrySynthetic Medicinal ChemistryOrganic SynthesisRetrosynthetic AnalysisAsymmetric Heterocycle SynthesisAsymmetric SynthesisIndole ChemistryIndole DerivativesIndole Synthesis
An expedient asymmetric total synthesis of aspidophytine is reported. A highly convergent strategy involving the sequential annulation of vinyl iodide 5 with indole 6 exploits varying modes of indole reactivity to provide aspidophytine in 23% over six steps from 5.
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A stereoselective synthesis of (Z)-1-iodo-1-alkenes
Gilbert Stork, Kang Zhao · Tetrahedron Letters · 1989 · 364 citations
Enantioselective Total Synthesis of Aspidophytine
Feng He, Yunxin Bo, Jason Altom et al. · Journal of the American Chemical Society · 1999 · 222 citations
Enantioselective Total Synthesis of Aspidophytine
Shinjiro Sumi, Koji Matsumoto, Hidetoshi Tokuyama et al. · Organic Letters · 2003 · 105 citations