A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

Ildo Nicoletti, Graziella Migliorati, Maria Cristina Pagliacci, +2

Journal of Immunological Methods

Flow CytometryBioanalysisApoptosisHematologyPathology +7

Identification and characterization of a new member of the TNF family that induces apoptosis

Steven R. Wiley, Ken Schooley, Pamela J. Smolak, +8

Immunity

InflammationCytokineSignaling PathwayMedicineReceptor Tyrosine Kinase +10

Tumoricidal activity of tumor necrosis factor–related apoptosis–inducing ligand in vivo

Henning Walczak, Robert E. Miller, K. Ariail, +13

Nature Medicine

InflammationAnti-inflammatoryMedicineApoptosisPharmacology +7

Safety and antitumor activity of recombinant soluble Apo2 ligand

Avi Ashkenazi, Roger Pai, Sharon Fong, +15

Journal of Clinical Investigation

Apo2l MrnaMedicinal ChemistryApo2l TreatmentAntitumor ActivityMedicine +11

Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor.

Frank Kischkel, Stefan Hellbardt, Iris Behrmann, +4

The EMBO Journal

Death-inducing Signaling ComplexSignal TransductionSignaling PathwayCytotoxicity-dependent Apo-1Apoptosis +6

Induction of Apoptosis by Apo-2 Ligand, a New Member of the Tumor Necrosis Factor Cytokine Family

Robert Pitti, Scot A. Marsters, Siegfried Ruppert, +3

Journal of Biological Chemistry

The Receptor for the Cytotoxic Ligand TRAIL

Guohua Pan, Karen O’Rourke, Arul M. Chinnaiyan, +4

Science

Control of TRAIL-Induced Apoptosis by a Family of Signaling and Decoy Receptors

James P. Sheridan, Scot A. Marsters, Robert Pitti, +10

Science

Signal TransductionSignaling PathwayG Protein-coupled ReceptorMedicineReceptor Tyrosine Kinase +13

An Antagonist Decoy Receptor and a Death Domain-Containing Receptor for TRAIL

Guohua Pan, Jian Ni, Ying-Fei Wei, +3

Science

Targeted Disruption of the Mouse Caspase 8 Gene Ablates Cell Death Induction by the TNF Receptors, Fas/Apo1, and DR3 and Is Lethal Prenatally

Eugene Varfolomeev, Marcus Schuchmann, Victor Luria, +15

Immunity

InflammationKnockout MouseSignal TransductionTnf ReceptorsSignaling Pathway +10