Asymmetric synthesis of trans- β -lactams through TiCl4-mediated addition to imines.

Asymmetric electrophilic amination: synthesis of .alpha.-amino and .alpha.-hydrazino acids with high optical purity

Cesare Gennari, Lino Colombo, Giorgio Bertolini · Journal of the American Chemical Society · 1986 · 217 citations

Natural Sciences, Chemistry, Medicinal Chemistry +11

N-Trimethylsilylimines: applications to the syntheses of .beta.-lactams

Deok Chan Ha, David J. Hart, Teng Yang · Journal of the American Chemical Society · 1984 · 118 citations

Natural Sciences, Chemistry, Medicinal Chemistry +6

New and effective route to β-lactams. The reaction of ketene silyl acetals with schiff bases promoted by titanium tetrachloride

Iwao Ojima, Shin‐ichi Inaba, Katsuhiko Yoshida · Tetrahedron Letters · 1977 · 110 citations

Pharmacy, Chemistry, Medicinal Chemistry +7

Asymmetric synthesis of .beta.-lactams and the carbapenem antibiotic (+)-PS-5

David J. Hart, Chih Shone. Lee, William H. Pirkle et al. · Journal of the American Chemical Society · 1986 · 83 citations

Natural Sciences, Chemistry, Medicinal Chemistry +9

Enantioselective synthesis of anti-.alpha.-methyl-.beta.-hydroxy esters through titanium tetrachloride-mediated aldol condensation

Cesare Gennari, Anna Bernardi, Lino Colombo et al. · Journal of the American Chemical Society · 1985 · 80 citations

Natural Sciences, Chemistry, Catalysis +8