Study of phosphorothioate-modified oligonucleotide resistance to 3′-exonuclease using capillary electrophoresis

Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide.

Paul C. Zamecnik, Mary L. Stephenson · Proceedings of the National Academy of Sciences · 1978 · 1.8K citations · Full text

Inhibition of replication and expression of human T-cell lymphotropic virus type III in cultured cells by exogenous synthetic oligonucleotides complementary to viral RNA.

Paul C. Zamecnik, John Goodchild, Y‐h. Taguchi et al. · Proceedings of the National Academy of Sciences · 1986 · 400 citations · Full text

Viral Replication, Immunology, Molecular Biology +16

Effect of phosphorothioate modification of oligodeoxynucleotides on specific protein binding.

David A. Brown, Shin Hyeok Kang, S. M. Gryaznov et al. · Journal of Biological Chemistry · 1994 · 340 citations · Full text

Phosphorothioate Modification, Phosphorothioate-modified Odns, Nucleic Acid Chemistry +15

Substrate Specificity and Kinetics of Degradation of Antisense Oligonucleotides by a 3′ Exonuclease in Plasma

Paul S. Eder, Rene J. DeVine, John M. Dagle et al. · Antisense Research and Development · 1991 · 285 citations

Bond Order and Charge Localization in Nucleoside Phosphorothioates

Perry A. Frey, R. Douglas Sammons · Science · 1985 · 278 citations