Concepedia

The ATM Kinase Induces MicroRNA Biogenesis in the DNA Damage Response

Xinna Zhang, Guohui Wan, Franklin G. Berger, Xiaoming He, Xiongbin Lu

Molecular Cell · 2011 · 237 citations · 39 references

Open access

Concepts

Life SciencesGeneticsMolecular BiologyDna RepairGene ExpressionTranscriptional RegulationDna DamageDna Damage SignalingDna Damage-induced ApoptosisMicrorna BiogenesisMicrorna BiologyMicrorna-mediated RegulationAtm ActivationAtm Kinase SignalingAtm-mediated Checkpoint SignalingDna Damage Response PathwaysDna Damage Response Signaling

References

39

The nuclear RNase III Drosha initiates microRNA processing

Yoontae Lee, Chiyoung Ahn, Jinju Han et al. · Nature · 2003 · 5.1K citations

Life Sciences, Genetics, Molecular Biology +11

MicroRNA genes are transcribed by RNA polymerase II

Yoontae Lee, Minju Kim, Jinju Han et al. · The EMBO Journal · 2004 · 4.3K citations · Full text

Life Sciences, Genetics, Molecular Biology +13

<i>miR-15</i> and <i>miR-16</i> induce apoptosis by targeting BCL2

Amelia Cimmino, George A. Calin, Muller Fabbri et al. · Proceedings of the National Academy of Sciences · 2005 · 3.5K citations · Full text

Life Sciences, Cancer Biology, Oncology +15

ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage

Shuhei Matsuoka, Bryan A. Ballif, Agata Smogorzewska et al. · Science · 2007 · 3.1K citations

Life Sciences, Cell Biology, Molecular Biology +17

A microRNA component of the p53 tumour suppressor network

Lin He, Xingyue He, Lee P. Lim et al. · Nature · 2007 · 2.7K citations

Life Sciences, Genetics, Molecular Biology +14