A zebrafish phenotypic assay for assessing drug-induced hepatotoxicity

The Vascular Anatomy of the Developing Zebrafish: An Atlas of Embryonic and Early Larval Development

Sumio Isogai, Masaharu Horiguchi, Brant M. Weinstein · Developmental Biology · 2001 · 913 citations

Life Sciences, Anatomy, Developmental Biology +16

High concordance of drug-induced human hepatotoxicity with in vitro cytotoxicity measured in a novel cell-based model using high content screening

Peter J. O’Brien, William Irwin, Dolores Diaz et al. · Archives of Toxicology · 2006 · 609 citations

Pharmacy, Pharmacology, Toxicology +16

The ECVAM International Validation Study on <i>In Vitro</i> Embryotoxicity Tests: Results of the Definitive Phase and Evaluation of Prediction Models

Elke Genschow, Horst Spielmann, Gabriele Scholz et al. · Alternatives to Laboratory Animals · 2002 · 380 citations

Pharmacy, Toxicology, Developmental Toxicology +9

Formation of the digestive system in zebrafish. I. liver morphogenesis

Holly A. Field, Elke A. Ober, Tobias Roeser et al. · Developmental Biology · 2003 · 371 citations

Life Sciences, Biology, Developmental Biology +12

Innate immune system plays a critical role in determining the progression and severity of acetaminophen hepatotoxicity

Zhang‐Xu Liu, Sugantha Govindarajan, Neil Kaplowitz · Gastroenterology · 2004 · 335 citations · Full text

Veterinary Medicine, Immunology, Pharmacology +16