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The identification of β-hydroxy carboxylic acids as selective MMP-12 inhibitors

Ian P. Holmes, Simon Gaines, Steve P. Watson, Olivier Lorthioir, Adam Walker, Suzanne J. Baddeley, Shane Herbert, Danielle Egan, M.A. Convery, Onkar Singh,

Bioorganic & Medicinal Chemistry Letters · 2009 · 16 citations · 6 references

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6

Matrix metalloproteinases: structures, evolution, and diversification

Irina Massova, Lakshmi P. Kotra, Rafael Fridman et al. · The FASEB Journal · 1998 · 775 citations

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Increase in macrophage elastase (MMP-12) in lungs from patients with chronic obstructive pulmonary disease

Sophie Molet, C. Belleguic, H. Léna et al. · Inflammation Research · 2005 · 247 citations

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A Selective Matrix Metalloprotease 12 Inhibitor for Potential Treatment of Chronic Obstructive Pulmonary Disease (COPD): Discovery of (<i>S</i>)-2-(8-(Methoxycarbonylamino)dibenzo[<i>b</i>,<i>d</i>]furan-3-sulfonamido)-3-methylbutanoic acid (MMP408)

Wei Li, Jianchang Li, Yuchuan Wu et al. · Journal of Medicinal Chemistry · 2009 · 104 citations · Full text

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Structural Differences of Matrix Metalloproteinases with Potential Implications for Inhibitor Selectivity Examined by the GRID/CPCA Approach

Gitte Elgaard Terp, Gabriele Cruciani, Inge Thøger Christensen et al. · Journal of Medicinal Chemistry · 2002 · 77 citations

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Structure-based design and synthesis of novel non-zinc chelating MMP-12 inhibitors

Anne‐Claude Dublanchet, Pierre Ducrot, Charles R. Andrianjara et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 69 citations · Full text

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