Concepedia

Adenovirus encoding HIV-1 Vpr activates caspase 9 and induces apoptotic cell death in both p53 positive and negative human tumor cell lines

Kar Muthumani, Donghui Zhang, Daniel S. Hwang, Sagar B. Kudchodkar, Nathanael S Dayes, Brijal Desai, Afshan S Malik, Joo-Sung Yang, Michael A. Chattergoon, Henry Maguire,

Oncogene · 2002 · 55 citations · 36 references

DOI

Concepts

References

36

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

Peng Li, Deepak Nijhawan, I. Imawati Budihardjo et al. · Cell · 1997 · 7.3K citations · Full text

, , +17

Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity

Julian He, S Choe, Robert Walker et al. · Journal of Virology · 1995 · 918 citations · Full text

, , +14

Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome.

Shinji Miyake, M Makimura, Yumi Kanegae et al. · Proceedings of the National Academy of Sciences · 1996 · 801 citations

, , +17

Evaluation of the concentration and bioactivity of adenovirus vectors for gene therapy

Nanette Mittereder, Keith L. March, B.C. Trapnell · Journal of Virology · 1996 · 777 citations · Full text

, , +13

HIV-1 Vpr increases viral expression by manipulation of the cell cycle: A mechanism for selection of Vpr in vivo

Wei Chun Goh, M E Rogel, C. Matthew Kinsey et al. · Nature Medicine · 1998 · 511 citations

, , +15