Total body irradiation causes residual bone marrow injury by induction of persistent oxidative stress in murine hematopoietic stem cells

Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses

Kai Rothkamm, Markus Löbrich · Proceedings of the National Academy of Sciences · 2003 · 1.6K citations · Full text

FoxOs Are Critical Mediators of Hematopoietic Stem Cell Resistance to Physiologic Oxidative Stress

Zuzana Tóthová, Ramya Kollipara, Brian J.P. Huntly et al. · Cell · 2007 · 1.5K citations · Full text

Reductive Stress, Developmental Biology, Medicine +11

Ink4a/Arf expression is a biomarker of aging

Janakiraman Krishnamurthy, Chad Torrice, Matthew R. Ramsey et al. · Journal of Clinical Investigation · 2004 · 1.4K citations · Full text

Developmental Biology, Aging, Ink4a/arf Locus +10

Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells

Keisuke Ito, Atsushi Hirao, Fumio Arai et al. · Nature Medicine · 2006 · 1.3K citations

Reactive Oxygen Species, Medicine, Stem Cell Mobilization +13

Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells

Keisuke Ito, Atsushi Hirao, Fumio Arai et al. · Nature · 2004 · 1.2K citations

Developmental Biology, Haematopoietic Stem Cells, Medicine +9