Total body irradiation causes residual bone marrow injury by induction of persistent oxidative stress in murine hematopoietic stem cells

Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses

Kai Rothkamm, Markus Löbrich · Proceedings of the National Academy of Sciences · 2003 · 1.6K citations

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FoxOs Are Critical Mediators of Hematopoietic Stem Cell Resistance to Physiologic Oxidative Stress

Zuzana Tóthová, Ramya Kollipara, Brian J.P. Huntly et al. · Cell · 2007 · 1.5K citations · Full text

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Ink4a/Arf expression is a biomarker of aging

Janakiraman Krishnamurthy, Chad Torrice, Matthew R. Ramsey et al. · Journal of Clinical Investigation · 2004 · 1.5K citations · Full text

Education, Cell Biology, Molecular Genetics +17

Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells

Keisuke Ito, Atsushi Hirao, Fumio Arai et al. · Nature Medicine · 2006 · 1.3K citations

Life Sciences, Cell Biology, Hematology +14

Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells

Keisuke Ito, Atsushi Hirao, Fumio Arai et al. · Nature · 2004 · 1.2K citations

Life Sciences, Cell Biology, Hematology +13