Concepedia

Negative feedback regulation of cellular antiviral signaling by RBCK1-mediated degradation of IRF3

Min Zhang, Yang Tian, Ruipeng Wang, Dong Gao, Yan Zhang, Feici Diao, Danying Chen, Zhonghe Zhai, Hong‐Bing Shu

Cell Research · 2008 · 146 citations · 35 references

DOI

Concepts

References

35

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

Mitsutoshi Yoneyama, Mika Kikuchi, Takashi Natsukawa et al. · Nature Immunology · 2004 · 3.9K citations

, , +16

Identification and Characterization of MAVS, a Mitochondrial Antiviral Signaling Protein that Activates NF-κB and IRF3

Rashu B. Seth, Lijun Sun, Chee-Kwee Ea et al. · Cell · 2005 · 3.3K citations · Full text

, , +10

IKKε and TBK1 are essential components of the IRF3 signaling pathway

Katherine A. Fitzgerald, Sarah M. McWhirter, Daniel C. Rowe et al. · Nature Immunology · 2003 · 2.7K citations

, , +6

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

Taro Kawai, Ken Takahashi, Shintaro Sato et al. · Nature Immunology · 2005 · 2.5K citations

, , +12

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

Etienne Meylan, Joseph Curran, Kay Hofmann et al. · Nature · 2005 · 2.4K citations · Full text

, , +13