Multiple chromosomal mechanisms generate an EWS/FLI1 or an EWS/ERG fusion gene in Ewing tumors

Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours

Olivier Delattre, Jessica Zucman‐Rossi, Béatrice Plougastel-Douglas et al. · Nature · 1992 · 1.9K citations

Life Sciences, Genetics, Molecular Genetics +17

The Ewing Family of Tumors -- A Subgroup of Small-Round-Cell Tumors Defined by Specific Chimeric Transcripts

Olivier Delattre, Jessica Zucman‐Rossi, Thomas Melot et al. · New England Journal of Medicine · 1994 · 1.1K citations · Full text

Medicine, Oncology, Pathology +15

A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS–family transcription factor, ERG

Poul H. Sorensen, Stephen L. Lessnick, Dolores López‐Terrada et al. · Nature Genetics · 1994 · 745 citations

Medicine, Genetics, Molecular Genetics +12

Combinatorial generation of variable fusion proteins in the Ewing family of tumours.

Thomas Melot, Chantal Desmaze, Jacques Ghysdael et al. · The EMBO Journal · 1993 · 539 citations · Full text

Medicine, Molecular Biology, Oncology +15

A variant Ewing's sarcoma translocation (7;22) fuses the EWS gene to the ETS gene ETV1.

In Sang Jeon, Jaimie N. Davis, Benjamin S. Braun et al. · PubMed · 1995 · 477 citations

Medicine, Genetics, Molecular Genetics +12