Concepedia

Combinatorial generation of variable fusion proteins in the Ewing family of tumours.

Thomas Melot, Chantal Desmaze, Jacques Ghysdael, Martine Peter, J M Zucker, Timothy J. Triche, Denise Sheer, Claude Turc‐Carel

The EMBO Journal · 1993 · 539 citations · 16 references

Open access

Concepts

MedicineMolecular BiologyOncologyCancer GeneticsMolecular OncologyOncogenesCancer GenomicsCancer Molecular PathologyEwing SarcomaGene Fusions In CancerOncogenic Fusion GenesDriver Fusion GenesEwsr1 Gene FusionsEwsr1-ets Fusion ProteinsGene Fusion OncoproteinsOncogenic Fusion ProteinsRecombinant Fusion ProteinsTumor-specific Fusion Genes

References

16

Molecular cloning: A laboratory manual

Prescott L. Deininger · Analytical Biochemistry · 1990 · 86.2K citations

Life Sciences, Molecular Biology, Molecular Genetics +11

Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours

Olivier Delattre, Jessica Zucman‐Rossi, Béatrice Plougastel-Douglas et al. · Nature · 1992 · 1.9K citations

Life Sciences, Genetics, Molecular Genetics +17

Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma

Anne Crozat, Pierre Åman, Nils Mandahl et al. · Nature · 1993 · 887 citations

Life Sciences, Molecular Biology, Oncology +11

Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation.

Win May, Mikhail L. Gishizky, Stephen L. Lessnick et al. · Proceedings of the National Academy of Sciences · 1993 · 577 citations

Medicine, Molecular Biology, Oncology +17

Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma

Terence H. Rabbitts, A. Förster, Rebecca C. Larson et al. · Nature Genetics · 1993 · 553 citations

Medicine, Molecular Biology, Oncology +16