Stephen L. Lessnick

Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation.

Win May, Mikhail L. Gishizky, Stephen L. Lessnick et al. · Proceedings of the National Academy of Sciences · 1993 · 577 citations

Medicine, Molecular Biology, Oncology +17

The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1.

Win May, Stephen L. Lessnick, Benjamin S. Braun et al. · Molecular and Cellular Biology · 1993 · 498 citations · Full text

Medicine, Molecular Biology, Oncology +16

β-Catenin–induced melanoma growth requires the downstream target <i>Microphthalmia</i>-associated transcription factor

Hans R. Widlund, Martin A. Horstmann, Edwin R. Price et al. · The Journal of Cell Biology · 2002 · 288 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

The Ewing's sarcoma oncoprotein EWS/FLI induces a p53-dependent growth arrest in primary human fibroblasts

Stephen L. Lessnick, Caroline S. Dacwag, Todd R. Golub · Cancer Cell · 2002 · 264 citations · Full text

Medicine, Molecular Genetics, Oncology +11

Multiple domains mediate transformation by the Ewing's sarcoma EWS/FLI-1 fusion gene.

Stephen L. Lessnick, Benjamin S. Braun, Christopher T. Denny et al. · PubMed · 1995 · 185 citations

Life Sciences, Genetics, Molecular Biology +12