Christopher T. Denny

A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS–family transcription factor, ERG

Poul H. Sorensen, Stephen L. Lessnick, Dolores López‐Terrada et al. · Nature Genetics · 1994 · 738 citations

Second Ewing, Transcriptional Regulation, Sarcoma Translocation +7

Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation.

Win May, Mikhail L. Gishizky, Stephen L. Lessnick et al. · Proceedings of the National Academy of Sciences · 1993 · 576 citations · Full text

Transcriptional Regulation, Systems Biology, Ewing Sarcoma +15

The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1.

Win May, Stephen L. Lessnick, Benjamin S. Braun et al. · Molecular and Cellular Biology · 1993 · 498 citations · Full text

Potent Transcriptional Activator, Transcriptional Regulation, Systems Biology +10

A variant Ewing's sarcoma translocation (7;22) fuses the EWS gene to the ETS gene ETV1.

In Sang Jeon, Jaimie N. Davis, Benjamin S. Braun et al. · PubMed · 1995 · 477 citations

Multiple domains mediate transformation by the Ewing's sarcoma EWS/FLI-1 fusion gene.

Stephen L. Lessnick, Benjamin S. Braun, Christopher T. Denny et al. · PubMed · 1995 · 185 citations