Complement inhibitors selectively attenuate injury following administration of cobra venom factor to rats

Intravascular activation of complement and acute lung injury. Dependency on neutrophils and toxic oxygen metabolites.

Gerd O. Till, K J Johnson, Robin Kunkel et al. · Journal of Clinical Investigation · 1982 · 550 citations · Full text

Life Sciences, Immunology, Pathobiology +17

Modification of the Inflammatory Response to Allergen Challenge after Exposure to Bacterial Lipopolysaccharide

Janet L. Wale Meri K.Tuli ć, Patrick G. Holt, Peter D. Sly · American Journal of Respiratory Cell and Molecular Biology · 2000 · 284 citations

Life Sciences, Immunology, Microbiology +13

Low-Molecular-Weight Peptidic and Cyclic Antagonists of the Receptor for the Complement Factor C5a

Angela M. Finch, A. K. Wong, Natalii J. Paczkowski et al. · Journal of Medicinal Chemistry · 1999 · 244 citations · Full text

Life Sciences, Immunology, Pharmacology +15

A small molecule C5a receptor antagonist protects kidneys from ischemia/reperfusion injury in rats

Thiruma V. Arumugam, Ian A. Shiels, Anna J. Strachan et al. · Kidney International · 2003 · 205 citations · Full text

Medicine, Nephrology, Pharmacology +11

Identification of a Selective Nonpeptide Antagonist of the Anaphylatoxin C3a Receptor That Demonstrates Antiinflammatory Activity in Animal Models

Robert S. Ames, Dennis Lee, James J. Foley et al. · The Journal of Immunology · 2001 · 201 citations · Full text

Medicine, Immunology, Pharmacology +17