Concepedia

Synthesis and activity of novel bile-acid conjugated glucocorticoid receptor antagonists

Steven J. Richards, Thomas W von Geldern, Peer B. Jacobson, Denise Wilcox, Phong Nguyen, Lars Öhman, Marie K. Österlund, Birgitta Gelius, Marlena Grynfarb, Annika Goos‐Nilsson,

Bioorganic & Medicinal Chemistry Letters · 2006 · 10 citations · 12 references

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References

12

The Three-dimensional Structures of Antagonistic and Agonistic Forms of the Glucocorticoid Receptor Ligand-binding Domain

Björn Kauppi, Clarissa G. Jakob, Mathias Färnegårdh et al. · Journal of Biological Chemistry · 2003 · 338 citations · Full text

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Glucocorticoids and insulin resistance: old hormones, new targets

Robert Andrews, Brian R. Walker · Clinical Science · 1999 · 266 citations

, , +16

Inactivation of the Glucocorticoid Receptor in Hepatocytes Leads to Fasting Hypoglycemia and Ameliorates Hyperglycemia in Streptozotocin-Induced Diabetes Mellitus

Christian Opherk, François Tronche, Christoph Kellendonk et al. · Molecular Endocrinology · 2004 · 200 citations · Full text

, , +15

Regio and stereospecific synthesis of 11β-substituted 19-norsteroids

A. Bèlanger, D. Philibert, Georges Teutsch · Steroids · 1981 · 131 citations

, , +9

Hepatic Glucocorticoid Receptor Antagonism Is Sufficient to Reduce Elevated Hepatic Glucose Output and Improve Glucose Control in Animal Models of Type 2 Diabetes

Peer B. Jacobson, Thomas W von Geldern, Lars Öhman et al. · Journal of Pharmacology and Experimental Therapeutics · 2005 · 77 citations · Full text

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