A two-step culture method starting with early growth factors permits enhanced production of functional dendritic cells from murine splenocytes

Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor.

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An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow

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Regenerative Medicine, Cell Therapy, Advanced Culture Method +13

Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products.

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Bacterial Products, Immunology, Immune Regulation +22

Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation.

Marina Cella, Doris Scheidegger, Kathrin Palmer-Lehmann et al. · The Journal of Experimental Medicine · 1996 · 2K citations · Full text

Cd40-cd40l Interaction, T-regulatory Cell, Immunology +18

Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells.

S E Macatonia, Nancy Hosken, Mark J. Litton et al. · The Journal of Immunology · 1995 · 1.5K citations