Concepedia

Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cells

Andrea Viale, Francesca Franco, Annette Orleth, Valeria Cambiaghi, Virginia Giuliani, Daniela Bossi, Chiara Ronchini, Simona Ronzoni, Ivan Muradore, Silvia Monestiroli,

Nature · 2008 · 303 citations · 36 references

DOI

Concepts

References

36

A biomarker that identifies senescent human cells in culture and in aging skin in vivo.

Goberdhan P. Dimri, X Lee, George Basile et al. · Proceedings of the National Academy of Sciences · 1995 · 7.4K citations · Full text

, , +15

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

Dominique Bonnet, John E. Dick · Nature Medicine · 1997 · 6.9K citations

, , +14

DNA Double-stranded Breaks Induce Histone H2AX Phosphorylation on Serine 139

Emmy P. Rogakou, Duane R. Pilch, Ann H. Orr et al. · Journal of Biological Chemistry · 1998 · 5.4K citations · Full text

, , +17

A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

Koichi Akashi, David Traver, Toshihiro Miyamoto et al. · Nature · 2000 · 2.6K citations

, , +12

Long-Term Lymphohematopoietic Reconstitution by a Single CD34-Low/Negative Hematopoietic Stem Cell

Masatake Osawa, Ken‐ichi Hanada, Hirofumi Hamada et al. · Science · 1996 · 2.1K citations

, , +17