Concepedia

Tandem prop-2-ynyl carbenoid–aldehyde insertion into zirconacycles

G. J. Gordon, Richard J. Whitby

Chemical Communications · 1997 · 12 citations · 14 references

DOI

Concepts

Abstract

Insertion of 1-lithio-1-chloroalk-2-ynes into zirconacycles gives cyclic zirconocene η 3 -prop-2-ynyl/allenyl complexes which afford useful organic products on protonation or Lewis acid induced addition of aldehydes.

References

14

Structure and chemistry of bis(cyclopentadienyl)-MLn complexes

Joseph W. Lauher, Roald Hoffmann · Journal of the American Chemical Society · 1976 · 1.1K citations

, , +6

Reaction of zirconocene dichloride with alkyllithiums or alkyl grignard reagents as a convenient method for generating a “zirconocene” equivalant and its use in zirconium-promoted cyclization of alkenes, alkynes, dienes, enynes, and diynes

Ei‐ichi Negishi, Fredrik Cederbaum, Tamotsu Takahashi · Tetrahedron Letters · 1986 · 562 citations

, , +7

Metal-promoted cyclization. 19. Novel bicyclization of enynes and diynes promoted by zirconocene derivatives and conversion of zirconabicycles into bicyclic enones via carbonylation

Ei‐ichi Negishi, Steven J. Holmes, James M. Tour et al. · Journal of the American Chemical Society · 1989 · 410 citations

, , +13

Patterns of Stoichiometric and Catalytic Reactions of Organozirconium and Related Complexes of Synthetic Interest

Ei‐ichi Negishi, Tamotsu Takahashi · Accounts of Chemical Research · 1994 · 388 citations

, , +10

Facile cleavage of the CβCβ′ bond of zirconacyclopentenes. Convenient method for selectively coupling alkynes with alkynes, nitriles, and aldehydes

Tamotsu Takahashi, Motohiro Kageyama, Ryuichiro Hara et al. · Tetrahedron Letters · 1993 · 169 citations

, , +6