E2F-1 Gene Therapy Induces Apoptosis and Increases Chemosensitivity in Human Pancreatic Carcinoma Cells

Biochemical and Cellular Effects of Roscovitine, a Potent and Selective Inhibitor of the Cyclin‐Dependent Kinases cdc2, cdk2 and cdk5

Laurent Meijer, Annie Borgne, Odile Mulner et al. · European Journal of Biochemistry · 1997 · 1.4K citations

Medicine, Cancer Biology, Oncology +15

Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis.

Xu Qin, David M. Livingston, William G. Kaelin et al. · Proceedings of the National Academy of Sciences · 1994 · 763 citations

Life Sciences, Genetics, Molecular Biology +15

Manipulation of Adenovirus Vectors

Frank L. Graham, L. Prevec · Humana Press eBooks · 2003 · 760 citations

Life Sciences, Microbiology, Molecular Biology +13

E2F-1 Functions in Mice to Promote Apoptosis and Suppress Proliferation

Seth J. Field, Fong‐Ying Tsai, Frank C. Kuo et al. · Cell · 1996 · 759 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +11

Tumor Induction and Tissue Atrophy in Mice Lacking E2F-1

Lili Yamasaki, Tyler Jacks, Roderick T. Bronson et al. · Cell · 1996 · 705 citations · Full text

Medicine, Cancer Biology, Oncology +16