A polarized Ca2+, diacylglycerol and STIM1 signalling system regulates directed cell migration

A Threshold Selection Method from Gray-Level Histograms

Nobuyuki Otsu · IEEE Transactions on Systems Man and Cybernetics · 1979 · 42.3K citations

Image Analysis, Machine Vision, Engineering +8

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

Grzegorz Grynkiewicz, Martin Poenie, Roger Y. Tsien · Journal of Biological Chemistry · 1985 · 21.7K citations · Full text

Ultrasensitive fluorescent proteins for imaging neuronal activity

Tsai‐Wen Chen, Trevor J. Wardill, Yi Sun et al. · Nature · 2013 · 6.9K citations · Full text

Engineering, Biomedical Imaging, Ultrasensitive Fluorescent Proteins +5

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.

Ole Thastrup, Peter J. Cullen, Bjørn K. Drøbak et al. · Proceedings of the National Academy of Sciences · 1990 · 3.3K citations · Full text

Ca2+ Homeostasis, Intracellular Ca2+ Stores, Cytoskeleton +19

STIM Is a Ca2+ Sensor Essential for Ca2+-Store-Depletion-Triggered Ca2+ Influx

Jen Liou, Man Lyang Kim, Won Do Heo et al. · Current Biology · 2005 · 2.1K citations · Full text

Physiology, Ca2+ Sensor Essential