Comparative study on human pharmacokinetics of activated ifosfamide and cyclophosphamide by a modified fluorometric test

Cyclophosphamide cystitis—Identification of acrolein as the causative agent

Peter J. Cox · Biochemical Pharmacology · 1979 · 573 citations

Inflammation, Autoimmune Disease, Gastrointestinal Pharmacology +5

Acrolein, the causative factor of urotoxic side-effects of cyclophosphamide, ifosfamide, trofosfamide and sufosfamide.

N Brock, Jurij Stekar, J. Pohl et al. · PubMed · 1979 · 187 citations

Non-toxic Additive Compound, Pharmacotherapy, Urotoxic Side-effects +19

Fluorometric determination of acrolein and related compounds with m-aminophenol

R.A. Alarcon · Analytical Chemistry · 1968 · 128 citations

Engineering, Altmetric Attention Score, Organic Chemistry +16

Isolation and mass spectral identification of blood metabolities of cyclophosphamide: Evidence for phosphoramide mustard as the biologically active metabolite

Robert F. Struck, Marion Kirk, Maxie H. Witt et al. · Journal of Mass Spectrometry · 1975 · 121 citations

The problem of specificity and selectivity of alkylating cytostatics; studies on N-2-chloroethylamido-oxazaphosphorines

N Brock, H. J. Hohorst · Journal of Cancer Research and Clinical Oncology · 1977 · 107 citations

Engineering, Bioorganic Chemistry, Biochemistry +6