N Brock

Acrolein, the causative factor of urotoxic side-effects of cyclophosphamide, ifosfamide, trofosfamide and sufosfamide.

N Brock, Jurij Stekar, J. Pohl et al. · PubMed · 1979 · 187 citations

Non-toxic Additive Compound, Pharmacotherapy, Urotoxic Side-effects +19

Metabolism of cyclophosphamide

N Brock, H. J. Hohorst · Cancer · 1967 · 160 citations · Full text

Secondary Metabolite, Toxicological Mechanism, Oxidative Stress +16

Chemotherapeutic Action of a Cyclic Nitrogen Mustard Phosphamide Ester (B 518-ASTA) in Experimental Tumours of the Rat

Herbert Arnold, F Bourseaux, N Brock · Nature · 1958 · 156 citations · Full text

Tumor Biology, Experimental Tumours, Oncology +8

Activation of cyclophosphamide in man and animals

N Brock, RH Gross, H. J. Hohorst et al. · Cancer · 1971 · 140 citations

Cyclophosphamide Activation Curves, Pharmacological Study, Medicine +14

Studies on the urotoxicity of oxazaphosphorine cytostatics and its prevention—III. Profile of action of sodium 2-mercaptoethane sulfonate (mesna)

N Brock, Jörg Pohl, Jurij Stekar et al. · European Journal of Cancer and Clinical Oncology · 1982 · 128 citations

Medicinal Chemistry, Biochemistry, Medicine +12