Apigenin induces apoptosis via extrinsic pathway, inducing p53 and inhibiting STAT3 and NFκB signaling in HER2-overexpressing breast cancer cells

Bid, a Bcl2 Interacting Protein, Mediates Cytochrome c Release from Mitochondria in Response to Activation of Cell Surface Death Receptors

Xu Luo, I. Imawati Budihardjo, Hua Zou et al. · Cell · 1998 · 3.6K citations · Full text

Mitophagy, Signal Transduction, Biochemistry +10

Role of Poly(ADP-ribose) Polymerase (PARP) Cleavage in Apoptosis

A. Hamid Boulares, Alexander G. Yakovlev, Vessela S. Ivanova et al. · Journal of Biological Chemistry · 1999 · 887 citations · Full text

Protein Function, Parp Cleavage, Biochemistry +11

Role for the p53 homologue p73 in E2F-1-induced apoptosis

Meredith S. Irwin, María C. Marín, Andrew C. Phillips et al. · Nature · 2000 · 706 citations

P53 Homologue P73, Medicine, Apoptosis +6

Suppression of inducible cyclooxygenase and inducible nitric oxide synthase by apigenin and related flavonoids in mouse macrophages

Yu‐Chih Liang, Ying-Tang Huang, Shu-Huei Tsai et al. · Carcinogenesis · 1999 · 565 citations

Chemoprevention Strategy, Lipid Peroxidation, Immunology +18

Mechanisms of p53-dependent apoptosis

Martin Schüler, Douglas R. Green · Biochemical Society Transactions · 2001 · 501 citations

Mitophagy, P53-dependent Apoptosis, Apoptosis +18