Sites and temporal changes of gangliosides GM1/GM2 storage in the Niemann–Pick disease type C mouse brain

Niemann-Pick C1 Disease Gene: Homology to Mediators of Cholesterol Homeostasis

Eugene D. Carstea, Jill A. Morris, Katherine Coleman et al. · Science · 1997 · 1.5K citations

Life Sciences, Genetics, Molecular Biology +17

Murine Model of Niemann-Pick C Disease: Mutation in a Cholesterol Homeostasis Gene

Stacie K. Loftus, Jill A. Morris, Eugene D. Carstea et al. · Science · 1997 · 807 citations

Life Sciences, Genetics, Molecular Biology +17

Ganglioside GM1 binds to the Trk protein and regulates receptor function.

Tatsuro Mutoh, Akira Tokuda, Toshiaki Miyadai et al. · Proceedings of the National Academy of Sciences · 1995 · 430 citations

Life Sciences, Neurobiology, Neuroscience +17

Transmembrane Molecular Pump Activity of Niemann-Pick C1 Protein

Joanna P. Davies, Fannie W. Chen, Yiannis A. Ioannou · Science · 2000 · 324 citations

Life Sciences, Biochemistry, Molecular Biology +17

Neurons in Niemann-Pick Disease Type C Accumulate Gangliosides as Well as Unesterified Cholesterol and Undergo Dendritic and Axonal Alterations

Mark Zervas, Kostantin Dobrenis, Steven U. Walkley · Journal of Neuropathology & Experimental Neurology · 2001 · 267 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17