Effects of farnesoid X receptor on the expression of the fatty acid synthetase and hepatic lipase

Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c

Mitsuhiro Watanabe, Sander M. Houten, Li Wang et al. · Journal of Clinical Investigation · 2004 · 1.3K citations · Full text

Carbohydrate response element binding protein directly promotes lipogenic enzyme gene transcription

Seiji Ishii, Katsumi Iizuka, Bonnie C. Miller et al. · Proceedings of the National Academy of Sciences · 2004 · 405 citations · Full text

Molecular Biology, Fatty Liver Disease, Insulin Signaling +21

Sterol Regulation of Fatty Acid Synthase Promoter

Mary K. Bennett, José M. López, Hugo B. Sanchez et al. · Journal of Biological Chemistry · 1995 · 330 citations · Full text

Metabolic Syndrome, Transcriptional Regulation, Systems Biology +14

Farnesoid X-Activated Receptor Induces Apolipoprotein C-II Transcription: a Molecular Mechanism Linking Plasma Triglyceride Levels to Bile Acids

Heidi R. Kast-Woelbern, Catherine Nguyen, Christopher J. Sinal et al. · Molecular Endocrinology · 2001 · 329 citations · Full text

Genetics, Fxr Ligands, Cholic Acid +21

Co-ordinate activation of lipogenic enzymes in hepatocellular carcinoma

Naoya Yahagi, Hitoshi Shimano, Kiyoshi Hasegawa et al. · European Journal of Cancer · 2005 · 246 citations

Hepatology, Biochemistry, Natural Sciences +7