Gene Expression in a Drosophila Model of Mitochondrial Disease

Daniel J.M. Fernández‐Ayala, Shanjun Chen, Esko Kemppainen, Kevin M.C. O’Dell, Howard T. Jacobs

PLoS ONE · 2010 · 75 citations · 92 references

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Abstract

These studies indicate that general and organ-specific metabolism is transformed in response to mitochondrial dysfunction, including digestive and absorptive functions, and give important clues as to how novel therapeutic strategies for mitochondrial disorders might be developed.

References

92