A brain serine/threonine protein kinase activated by Cdc42 and Rac1

Edward Manser, Thomas Leung, Harfizah Salihuddin, +2

Nature

Signal TransductionMolecular NeuroscienceMolecular PhysiologySignaling PathwayReceptor Tyrosine Kinase +6

Activation of Rac and Cdc42 by Integrins Mediates Cell Spreading

Leo Price, Jie Leng, Martin A. Schwartz, +1

Molecular Biology of the Cell

Cell AdhesionImmunologyCytoskeletonCellular PhysiologyIntegrin-dependent Adhesion +15

Integrin-mediated Signals Regulated by Members of the Rho Family of GTPases

Edwin Clark, W G King, Joan S. Brugge, +2

The Journal of Cell Biology

Unconventional Rac-GEF activity is mediated through the Dock180–ELMO complex

Enrico Brugnera, Lisa B. Haney, Cynthia Grimsley, +7

Nature Cell Biology

Signal TransductionNatural SciencesUnconventional Rac-gef ActivityMolecular BiologyBiomolecular Interaction +1

CED-12/ELMO, a Novel Member of the CrkII/Dock180/Rac Pathway, Is Required for Phagocytosis and Cell Migration

Tina L. Gumienny, Enrico Brugnera, Annie‐Carole Tosello‐Trampont, +12

Cell

Cell SignalingMedicinePathogenesisImmunologyCell Trafficking +7

Activation of Rac1 by a Crk SH3-binding protein, DOCK180

Etsuko Kiyokawa, Yuko Hashimoto, Shin Kobayashi, +3

Genes & Development

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity

Jean‐François Côté, Kristiina Vuori

Journal of Cell Science

Mammalian Dock180 ProteinGeneticsMolecular BiologyMolecular GeneticsSignaling Pathway +16

αvβ5 integrin recruits the CrkII–Dock180–Rac1 complex for phagocytosis of apoptotic cells

Matthew L. Albert, Jong-Ii Kim, Raymond B. Birge

Nature Cell Biology

Signal TransductionApoptosisImmunologyCell DeathαVβ5 Integrin +7

Rhotekin, a New Putative Target for Rho Bearing Homology to a Serine/Threonine Kinase, PKN, and Rhophilin in the Rho-binding Domain

Tim Reid, Tomoyuki Furuyashiki, Toshimasa Ishizaki, +6

Journal of Biological Chemistry

Molecular BiologyRho Bearing HomologyRho-binding DomainProtein ExpressionProteomics +20

DOCK180, a Major CRK-Binding Protein, Alters Cell Morphology upon Translocation to the Cell Membrane

Hideki Hasegawa, Etsuko Kiyokawa, Shinya Tanaka, +5

Molecular and Cellular Biology

Protein AssemblyCrk Sh3Molecular Biology180-Kda ProteinCellular Physiology +18