RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

Edward Manser, Thomas Leung, Harfizah Salihuddin et al. · Nature · 1994 · 1.5K citations

Signal Transduction, Molecular Neuroscience, Molecular Physiology +8

Activation of Rac and Cdc42 by Integrins Mediates Cell Spreading

Leo Price, Jie Leng, Martin A. Schwartz et al. · Molecular Biology of the Cell · 1998 · 638 citations · Full text

Cell Adhesion, Immunology, Cytoskeleton +17

Integrin-mediated Signals Regulated by Members of the Rho Family of GTPases

Edwin Clark, W G King, Joan S. Brugge et al. · The Journal of Cell Biology · 1998 · 606 citations · Full text

Unconventional Rac-GEF activity is mediated through the Dock180–ELMO complex

Enrico Brugnera, Lisa B. Haney, Cynthia Grimsley et al. · Nature Cell Biology · 2002 · 568 citations

Signal Transduction, Natural Sciences, Unconventional Rac-gef Activity +3

CED-12/ELMO, a Novel Member of the CrkII/Dock180/Rac Pathway, Is Required for Phagocytosis and Cell Migration

Tina L. Gumienny, Enrico Brugnera, Annie‐Carole Tosello‐Trampont et al. · Cell · 2001 · 561 citations · Full text

Cell Signaling, Medicine, Pathogenesis +9