Evaluation of cellular uptake and intracellular trafficking as determining factors of gene expression for amino acid-substituted gemini surfactant-based DNA nanoparticles

The effect of particle design on cellular internalization pathways

Stephanie E. A. Gratton, Patricia A. Ropp, Patrick D. Pohlhaus et al. · Proceedings of the National Academy of Sciences · 2008 · 2.9K citations · Full text

Nanoparticles, Tissue Engineering, Colloidal Material +21

Size-dependent internalization of particles via the pathways of clathrin- and caveolae-mediated endocytosis

Joanna Rejman, Volker Oberle, Inge S. Zuhorn et al. · Biochemical Journal · 2004 · 2.8K citations · Full text

Molecular Biology, Extracellular Microvesicles, Cytoskeleton +22

Cellular and Molecular Barriers to Gene Transfer by a Cationic Lipid

Joseph Zabner, A Fasbender, Tom Moninger et al. · Journal of Biological Chemistry · 1995 · 1.4K citations · Full text

Molecular Biology, Gene Delivery, Lipid Movement +16

Mis-assembly of clathrin lattices on endosomes reveals a regulatory switch for coated pit formation.

L H Wang, Karen G. Rothberg, Richard G.W. Anderson · The Journal of Cell Biology · 1993 · 1.2K citations · Full text

Molecular Biology, Cytoskeleton, Cellular Physiology +16

Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses

Alexandre Arcaro, Matthias P. Wymann · Biochemical Journal · 1993 · 1.1K citations · Full text

Immunology, Ptdinsp3 Production, Inflammation +17