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Epidermal growth factor receptor status and persistent activation of Akt and p44/42 MAPK pathways correlate with the effect of cetuximab in head and neck and colon cancer cell lines

Takashi Yamatodani, Lars Ekblad, Elisabeth Kjellén, Anders Johnsson, Hiroyuki Mineta, Johan Wennerberg

Journal of Cancer Research and Clinical Oncology · 2008 · 47 citations · 30 references

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30

New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening

Philip Skehan, Ritsa Storeng, Dominic A. Scudiero et al. · JNCI Journal of the National Cancer Institute · 1990 · 9.7K citations

Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

Sandeep Robert Datta, Henryk Dudek, Xu Tao et al. · Cell · 1997 · 5.7K citations · Full text

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Cetuximab Monotherapy and Cetuximab plus Irinotecan in Irinotecan-Refractory Metastatic Colorectal Cancer

David Cunningham, Yves Humblet, Salvatore Siena et al. · New England Journal of Medicine · 2004 · 5K citations · Full text

<i>KRAS</i> Mutation Status Is Predictive of Response to Cetuximab Therapy in Colorectal Cancer

Astrid Lièvre, Jean‐Baptiste Bachet, Delphine Le Corre et al. · Cancer Research · 2006 · 2.2K citations

Cyclin D1 Expression Is Regulated Positively by the p42/p44 and Negatively by the p38/HOG Pathway

Josée N. Lavoie, Gilles L’Allemain, Anne Brunet et al. · Journal of Biological Chemistry · 1996 · 1.2K citations · Full text

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