Concepedia

T0901317 is a dual LXR/FXR agonist

Keith A. Houck, Kristen M. Borchert, Christopher D. Hepler, Jeffrey S. Thomas, Kelli Bramlett, Laura F. Michael, Thomas P. Burris

Molecular Genetics and Metabolism · 2004 · 184 citations · 18 references

DOI

Concepts

References

18

A Regulatory Cascade of the Nuclear Receptors FXR, SHP-1, and LRH-1 Represses Bile Acid Biosynthesis

Bryan Goodwin, Stacey A. Jones, Roger R. Price et al. · Molecular Cell · 2000 · 1.9K citations · Full text

, , +16

An oxysterol signalling pathway mediated by the nuclear receptor LXRα

Bethany A. Janowski, Patricia J. Willy, Thota Rama Devi et al. · Nature · 1996 · 1.7K citations

, , +11

Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ

Joyce J. Repa, Guosheng Liang, Jiafu Ou et al. · Genes & Development · 2000 · 1.7K citations · Full text

, , +16

Role of LXRs in control of lipogenesis

Joshua R. Schultz, Hua Tu, Alvin Luk et al. · Genes & Development · 2000 · 1.7K citations · Full text

, , +17

Molecular Basis for Feedback Regulation of Bile Acid Synthesis by Nuclear Receptors

Timothy T. Lu, Makoto Makishima, Joyce J. Repa et al. · Molecular Cell · 2000 · 1.5K citations · Full text

, , +17