Identification and kinetics of a ?-glucuronide metabolite of SN-38 in human plasma after administration of the camptothecin derivative irinotecan

Clinical pharmacokinetics; concepts and applications

General Pharmacology The Vascular System · 1989 · 2.2K citations

Pharmacy, Clinical Pharmacokinetics, Pharmacokinetics +12

A kinetic and Mechanistic Study of the Hydrolysis of Camptothecin and Some Analogues

Julianne Fassberg, Valentino J. Stella · Journal of Pharmaceutical Sciences · 1992 · 464 citations

Life Sciences, Biochemistry, Chemistry +12

Phase I and pharmacokinetic trial of weekly CPT-11.

Mace L. Rothenberg, John G. Kuhn, Howard A. Burris et al. · Journal of Clinical Oncology · 1993 · 303 citations

Medicine, Oncology, Pharmacology +16

Metabolism and pharmacokinetics of the camptothecin analogue CPT-11 in the mouse.

N Kaneda, Hiroko Nagata, T Furuta et al. · PubMed · 1990 · 293 citations

Pharmacy, Pharmacokinetics, Pharmacology +11

CPT-11 Converting Enzyme from Rat Serum: Purification and Some Properties.

Tatsuya Tsuji, Norimasa Kaneda, Kunio KADO et al. · Journal of Pharmacobio-Dynamics · 1991 · 139 citations · Full text

Life Sciences, Biochemistry, Pharmacology +16